ExpressArt® RNA Isolation Kits: unique technology for RNA isolation
ExpressArt® mRNA Amplification Kits: patented technology for universal amplification of even highly degraded mRNAs
Patented technology for bacterial mRNA amplification
Picograms of total RNA input sufficient
Possible applications Reliable high quality RNA-Isolation from FFPE-material Universal pre-amplification of mRNAs for Transcriptome Analysis Universal pre-amplification of mRNAs for Next generation Sequencing Analysis (NGS)
Functional mRNAs
Customized functional mRNAs from any sequence
Highly modified or unmodified available
cGMP-API-Production
Any Scale available (from ng to mg)
Highly standardized AmpTec workflow
ISO 13485 and cGMP grade available, cGMP-API production available
Possible applications Highly specific vaccination Individualized tumor therapy with tissue-specific and patient-specific tumor markers/antigens (anti-viral therapy) Stem cells by cellular reprogramming Cell therapy with in vitro generated tissue autologous, patient-derived tissue cells (see Quabius & Krupp, 2014 )
Customized long RNAs and DNAs from any sequence for in vitro diagnostics or companion diagnostics
High quality IVT-RNA and DNA in any length and scale
Highly standardized AmpTec workflow
ISO 13485 and cGMP grade available
Possible applications Reference material for the development of in vitro diagnostic assays Internal control RNA for performance control (e.g. RNA isolation, reverse transcription and qPCR amplification / detection Positive control RNAs for controlling high assay qualities
Direct dsRNA synthesis procedure, not by annealing of two ssRNAs
Highly standardized AmpTec workflow
Possible applications Double-strand RNA (dsRNA) as tool for gene-specific silencing of gene expression Long dsRNA is substantially more effective than short dsRNA Indirect introduction of long dsRNA in diverse organisms Direct injection of long dsRNA in oysters as prominent example
